Cardiovascular disease (CVD) mortality in the United Kingdom has decreased significantly over the past 30 years, but its prevalence has shown little change, and major differences exist in the burden of CVD among the four constituent countries and between men and women, a review has found.
Women taking combined hormone replacement therapy (HRT) are 2.7 times more likely to develop breast cancer than non-users, and the risk may increase with longer use, a study published in the British Journal of Cancer has found.
The researchers, from the Institute of Cancer Research in London, said that previous studies may have substantially underestimated the risk of breast cancer from combined HRT, as they did not update information about a woman’s HRT use or analyse accurately to allow for her age at menopause.
The new research was part of the Breast Cancer Now Generations Study, which is following more than 100 000 women for 40 years to investigate the causes of breast cancer.
Using paracetamol to treat fever or pain is no more likely than ibuprofen to exacerbate asthma in children with mild persistent asthma, a randomised trial has shown (in the New England Journal of Medicine).
Observational data have previously linked paracetamol and asthma symptoms to decreased lung function, so some doctors have recommended avoiding the drug in children with asthma. But data from randomised trials have been limited.
Two drugs currently provided under the Cancer Drugs Fund (CDF) should cease to be available because they are not cost effective, the National Institute for Health and Care Excellence (NICE) has concluded.
Everolimus for breast cancer (Afinitor, Novartis) and ibrutinib for mantle cell lymphoma (Imbruvica, Janssen) do not meet the grade, says NICE in draft guidance now open for consultation.
Older patients with type 2 diabetes who consume dietary omega 3 fatty acids equivalent to at least two weekly servings of oily fish have a significantly lower risk of sight threatening diabetic retinopathy than those who eat less, a prospective observational study has shown.1
Diabetic retinopathy is a major cause of vision loss in older people. The pathogenesis is not fully understood, but inflammation, oxidative stress, and microvascular changes play important roles…
The latest edition of our bulletin for Critical Care has been published here
The new edition of our breast surgery bulletin has been published here
The library currently has a free trial to the internurse and MAHcomplete e-journal collections.
Internurse is the UK’s largest collection of peer-reviewed nursing content, and home of the British Journal of Nursing. Internurse covers primary and secondary care settings as well as the whole spectrum of specialist nursing practice including cardiology, neuroscience, mental health, palliative care and wound care.
Access the collection with your East Cheshire NHS Athens account: Login to Athens. Select ‘MAG Online Library’ from the list of resources.
If you would like to find out more or have any questions please phone us on 01625 661362 or send us an email.
General practice leaders have called on the government and the General Medical Council to correct the “anachronistic anomaly” whereby GP postgraduate training remains unrecognised as a medical specialty in the United Kingdom.
In a joint statement,
GP leaders from the BMA and the Royal College of General Practitioners (RCGP) from across the four UK nations said that this recognition was “long overdue” given the rigorous training and examination that GPs undergo.
“Think sepsis” in any person with suspected infection
Sepsis may present with non-specific symptoms and signs and without fever
Have a high index of suspicion of sepsis in those who are aged <1 year or >75 years, pregnant, or immunocompromised, and those who have a device or line in situ or have had recent surgery
Use risk factors and any indicators of clinical concern to decide if full assessment is required
Offer people at high risk of sepsis broad spectrum antibiotics and intravenous fluids in hospital
Need to understand health research better? Not sure how to assess the quality of the research you have found? This new tool found on the Understanding Health Research website may help you.
It has been created, by Glasgow University’s social and public health sciences unit (and other collaborators) help people understand published health research and distinguish between “good” and “bad” studies.
The aims of the tool are to allow lay and professional audiences to understand how to assess the quality of research evidence, raise awareness of what evidence is and how it is generated, teach or reaffirm critical health literacy skills
What if…………every patient were to have their genome mapped?
Read this short article to discover the potential for targeted treatments.
– Just one in a series of short articles on hypothetical scenarios, published by Kings Fund.
Easy to read, the articles are intended to encourage new thinking and debate about possible future scenarios that could fundamentally change health and care.
The essays cover three themes: the NHS and society; medicine, data and technology; and how the NHS works.
See the full collection of Kings Fund Essays exploring hypothetical scenarios in healthcare here.
The Kings Fund has published several items including an article by Chris Naylor which considers the prospects for better integration of mental health care with general practice and the importance of integrated care provision. This follows on from the recent publication of NHS England’s implementation plan for The five year forward view for mental health.
The Kings Fund report- Bringing together physical and mental health: a new frontier for integrated care describes examples of services that have developed a more integrated approach.
The Library & Knowledge Service purchased a large number of new books last month ~ view a selection of the new titles here. All members of East Cheshire NHS Trust staff, students on placement and volunteers are able to borrow books from the Library. Contact the Library for more information: firstname.lastname@example.org / 01625 66 1362.