Eyes on Evidence update: Issue 48 – April 2013

Changes at NICE

Since you last received Eyes on Evidence our name has changed to the National Institute for Health and Care Excellence, to reflect our new role and responsibilities. NICE’s role is to improve outcomes for people using the NHS and other public health and social care services.

Infectious diseases among homeless populations

The prevalence of infectious diseases, such as tuberculosis, HIV and hepatitis C, in homeless populations is significantly higher than in the general population. However, figures show much local variation raising questions about the need for a more locally-based response.

Risk of abuse in disabled children A systematic review of studies from across the world suggests that more than a quarter of children with disabilities will experience abuse within their lifetimes and that children with disabilities are 3 to 4 times more likely to be victims of abuse than their peers without disabilities.

Rheumatoid factor and risk of future rheumatoid arthritis A cohort study reports that raised levels of rheumatoid factor are associated with an increased risk of developing rheumatoid arthritis. Although treating pre-rheumatoid is currently of unproven value, this study suggests it might be possible in the future.

Heart failure: effects of aldosterone antagonists and renin-angiotensin antagonists on mortality An observational study in people admitted to hospital with heart failure (HF) with reduced ejection fraction finds that aldosterone antagonists reduce readmissions for HF but have no effect on mortality and increase the risk of admission with hyperkalaemia. Another observational study in people with HF with preserved ejection fraction finds that angiotensin converting enzyme inhibitors or angiotensin receptor blockers reduced all-cause mortality.

Grapefruit–drug interactions A review article details the evidence for a pharmacokinetic interaction between grapefruit and certain drugs, and the potential clinical consequences of this.

Case studies from the Quality Improvement Productivity and Prevention (QIPP) Collection

The QIPP Collection highlights examples of local best practice, demonstrating how NHS organisations have implemented new practices that have both cut costs and improved quality. We highlight 2 new examples:

Evidence Updates
NICE has recently published Evidence Updates on:

  • Diabetic foot problems
  • Hip fracture
  • Caesarean section
  • Anaphylaxis

 

New Evidence Updates from NICE

Evidence Updates on Hip Fracture and Diabetic foot problems have been published.nice_news

NICE Evidence Updates help to reduce the need for individuals, managers and commissioners to search for new evidence, and keep health and social care professionals up-to-date with new research. While Evidence Updates do not replace current accredited guidance and do not provide formal recommendations, they do highlight new evidence that health and social care professionals may wish to consider alongside current guidance.

The new Evidence Updates focus on a summary of selected new evidence relevant to NICE clinical guideline 124 ‘The management of hip fracture in adults’ (2011) and a summary of selected new evidence relevant to NICE clinical guideline

119 ‘Inpatient management of diabetic foot problems’ (2011)

An Evidence Update Advisory Group, comprised of topic experts, reviewed the prioritised evidence and provided a commentary.