Initial drug treatment in Parkinson’s disease

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Parkinson’s disease is a progressive neurodegenerative disorder characterised by tremor, rigidity, bradykinesia, and a wide spectrum of non-motor symptoms including sleep disorders, hyposmia, bladder and bowel dysfunction, fatigue, dementia, and other neuropsychiatric symptoms.

Although the disease has no cure, available treatments effectively control motor symptoms and improve quality of life. Several drug classes are licensed for use as monotherapy in early Parkinson’s disease and adjuvant therapy in later disease