With increasing use of electronic cigarettes (e-cigarettes) and other electronic nicotine delivery systems (ENDS) globally, the debate surrounding the potential harms or benefits may shift to ensuring that the devices are manufactured, marketed, and sold according to standards that reduce harm and promote health. Burns from overheating or explosions of ENDS are an emerging and under-researched concern. In light of the recent ruling that grants the US Food and Drug Administration authority to regulate ENDS1 and as their use becomes widespread worldwide, a clinical, public health, and regulatory framework to reduce ENDS related burns is needed.
Adolescents and young adults who use electronic cigarettes are more likely to progress to smoking tobacco cigarettes than those who do not, shows a small US study that researchers say supports regulations to limit sales and reduce the appeal of e-cigarettes to young people.
The study, published in JAMA Pediatrics, followed up a nationally representative sample of 694 teenagers and young adults aged 16 to 26 who had never smoked. Their attitudes showed that they were not susceptible to smoking cigarettes because they had responded “definitely no” when asked whether they would try a cigarette offered by a friend or whether they believed that they would smoke a cigarette within the next year.
This month in Eyes on Evidence
E-cigarette awareness and use to quit smoking
A survey suggests that awareness and use of e-cigarettes has increased over the past few years, but a randomised controlled trial indicates that the products are only modestly effective at helping people to quit smoking.
Beta-2 agonists and exercise-induced asthma
A Cochrane review has assessed the effects of short and long-acting beta-2 agonists for the prevention of exercise-induced asthma in adults and children; the majority of included studies assessed the effect of a single dose of a beta-2 agonist. The Medicines and Healthcare Products Regulatory Agency has previously issued advice recommending that long-acting beta-2 agonists should not be prescribed for the relief of exercise-induced asthma symptoms in the absence of regular inhaled corticosteroids.
Blood pressure control with home telemonitoring and pharmacist management
A US-based cluster randomised trial indicates that home telemonitoring with pharmacist medication management provides better blood pressure control than usual primary care, even once telemonitoring has finished.
Risk factors for congenital abnormalities
A prospective study of a UK multi-ethnic birth cohort suggests that consanguinity is a major risk factor for congenital abnormalities, in particular in children of parents of Pakistani origin.
Antidepressant use late in pregnancy and risk of postpartum haemorrhage
A cohort study of women with low income in the USA suggests that use of antidepressants near delivery is associated with an increased risk of postpartum haemorrhage.
CT scans in childhood or adolescence and risk of cancer
A population-based cohort study in Australia suggests that people who undergo CT scans in childhood or adolescence are at increased risk of developing solid, lymphoid and haematopoietic cancers.
NICE has recently published an Evidence Update on:
Alcohol-use disorders: preventing harmful drinking
- Italian government sets up a stem cell trial to assuage public demands
- Doctors call for countries to step up the fight against rheumatic heart disease
- High dose NSAIDs may double the risk of heart attacks and heart failure, says new study
- Indian generics manufacturer Ranbaxy agrees to pay $500m to settle US fraud and drug safety charges
- Governments must agree unified approach to use of e-cigarettes, report says
- Dutch doctors to receive more clarity over use of advance euthanasia directives for patients with dementia
- Spend less on drug enforcement and more on treating hepatitis C, say campaigners
- WHO agrees to set up body to act on non-communicable diseases
- Number, type, and availability of new drugs are on the increase in Europe
- WHA calls for five demonstration projects on health research relevant to the developing world
- Government to increase number of GPs and emergency medicine doctors
- Workplace wellness programs show little benefit, US report says
- Critical care patients have major health and financial problems 12 months after discharge, finds study
- WHO to probe claims that Dutch scientists restricted access to novel coronavirus