Combined HRT may raise breast cancer risk, study finds

Women taking combined hormone replacement therapy (HRT) are 2.7 times more likely to develop breast cancer than non-users, and the risk may increase with longer use, a study published in the British Journal of Cancer has found.

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The researchers, from the Institute of Cancer Research in London, said that previous studies may have substantially underestimated the risk of breast cancer from combined HRT, as they did not update information about a woman’s HRT use or analyse accurately to allow for her age at menopause.

The new research was part of the Breast Cancer Now Generations Study, which is following more than 100 000 women for 40 years to investigate the causes of breast cancer.

HRT increases risk of blood clots and stroke, finds new analysis

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Hormone replacement therapy (HRT) offers women no protection against having or dying from a myocardial infarction while increasing the risk of blood clots and stroke, a new analysis published by the Cochrane Collaboration has shown.

But, complicating the message, a subgroup analysis of women who were given HRT below the age of 60 or within 10 years of the menopause did show a reduction in the risk of myocardial infarction and death from any cause while also showing an increased risk of blood clots and possibly stroke