Peptides that form amyloid plaques in Alzheimer’s may be transmissible, study finds

Amyloid β, the peptide that forms amyloid plaques in the brains of people with Alzheimer’s disease, may be transmissible through medical treatments such as blood products and surgical instruments, a small UK study published in Nature has shown.

Researchers working on iatrogenic Creutzfeldt-Jakob disease (iCJD) unexpectedly found four autopsy cases with moderate to severe deposition of amyloid β in the grey matter of the brain typical of that seen in Alzheimer’s disease. They also found the peptide in the blood vessel walls deposited in a way that was characteristic of cerebral amyloid angiopathy.

Click for article

Click for article

New ejournals available

Resource Reminder

Until March 2015 staff and students at East Cheshire Trust can access the NATURE NHS FINCH COLLECTION which includes the following subject areas:

  • Chemistry
  • Clinical Practice and Research
  • Earth and Environment
  • Life Sciences: Includes British Journal of Cancer, British Dental Journal, American Journal of Gastroenterology, Clinical Pharmacology and Therapeutics, European Journal of Clinical Nutrition, International Journal of Obesity,Eye and many more.

You will need an Athens account before going to:

  • Login at http://www.nature.com/
  • Select Login via Athens
  • From the top of the Home page browse either by publication or by
    subject

Click here now to view the collection