Paracetamol is no more likely to exacerbate asthma in children than ibuprofen, shows study

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Using paracetamol to treat fever or pain is no more likely than ibuprofen to exacerbate asthma in children with mild persistent asthma, a randomised trial has shown (in the New England Journal of Medicine).

Observational data have previously linked paracetamol and asthma symptoms to decreased lung function, so some doctors have recommended avoiding the drug in children with asthma. But data from randomised trials have been limited.

Journal choice: JRSM v NEJM

Clinical staff were recently emailed to state their preference between these 2 esteemed journals. The Staff Library is able to fund one but sadly, not both. If you haven’t already voted you can still contact us and let us know your preference –
Journal of the Royal Society for Medicine or New England Journal of Medicine.

Please email us at janread@nhs.net or ecn-tr.stafflibrary@nhs.net marking your choice clearly JRSM or NEJM.

The closing date is 19 November.

Thank you

eTOC pilot service

A new service from The Staff Libraryjama

From 16 June we will be piloting our electronic table of contents service (eTOC) which uses emails to update the recipient of the latest content of their favourite journals.  Initially we are focussing on just two of the hundreds of online publications – New England Journal of Medicine (NEJM) and the Journal of American Medical Association (JAMA). However, if there is sufficient interest we hope to extend this to include requests and other quality journals.

Sample content would look like this – following the links would bring up the article abstract. If we do not have a subscription to the journal, we would order the article for you as part of our inter-library loan service.

nejmNew England Journal of Medicine (24 new articles):

Tattoos and Sarcoidosis
Spot Diagnosis
Pharmacology and the Treatment of Complicated Skin and Skin-Structure Infections
Management of Skin Abscesses
Pregnancy and Infection
Adverse Health Effects of Marijuana Use

If you are interested in taking part or would like to know more, please contact Jan Read or email the Staff Library on 66 1362. Thank you.

Warfarin v Aspirin – new research published

“Aspirin could be as effective as more expensive drugs for heart failure patients with a normal heart rhythm, according to researchers.

Their study on more than 2,000 patients, published in the New England Journal of Medicine, said aspirin was as effective as the commonly prescribed drug warfarin.   It said each drug had risks, but they had similar benefits overall.” (BBC News)

Read the full findings at http://www.nejm.org/doi/pdf/10.1056/NEJMe1202504

“The benefit of warfarin in reducing the rate of ischemic stroke was offset by an increase in the rate of major bleeding (1.78 events per 100 patient-years with warfarin vs. 0.87 events per 100 patient-years with aspirin, P<0.001; number needed to harm, 110), although there was no excess of intracerebral bleeding events (0.12 events per 100 patient-years with warfarin and 0.05 events per 100 patient-years with aspirin, P = 0.35).”