Common painkillers and kidney failure in children

Journal of Pediatrics

Date published: 28/01/2013 17:18

Summary by: Angela Bennett

A retrospective chart review, being published in the Journal of Paediatrics reports on the number of children diagnosed with acute kidney injury caused by NSAIDs in one U.S hospital over an 11 and a half year span.

Out of 1015 children that presented with acute kidney injury, 27 were identified to have NSAID-associated acute kidney injury (2.7%). Seventy-eight percent of the 27 patients had been using NSAIDs for less than 7 days. None of the patients died or developed permanent kidney failure, but 30% of the children had evidence of mild chronic kidney damage persisting after recovery from the episode of acute kidney injury.

Thachil J.; Whitehead G.A; Indian Journal of Pediatrics; September 2012,

Clotting screen requests in pediatrics – an article published in Indian Journal of Pediatrics, September 2012, vol./is. 79/9(1233-1235), 0019- 456;0973-7693 (September 2012)

Author(s): Thachil J.; Whitehead G.A.

Institution: (Thachil) Department of Hematology, Royal Liverpool University Hospital, Prescot Street, Liverpool, L7 8XP,  (Whitehead) Department of Child Health, Macclesfield General Hospital, Macclesfield, United Kingdom
Language: English

blood sample

Abstract: Coagulation parameters are routinely requested among all age-groups in pediatrics to identify abnormalities which may contribute to bleeding manifestations or thrombotic complications. These results are vital especially in the management of sick children although in some cases, they may be helpful in identifying those with inherited bleeding disorders and to confirm or exclude non-accidental injury. Despite the usefulness of these screening tests, it is important that the professionals who are responsible for the care of children interpret the results of these tests in the most accurate manner to avoid unnecessary further investigations and inappropriate management.

Dr. K C Chaudhuri Foundation 2011.
Country of Publication: India
Publisher: Springer India (Barakhamba Road 110001, New Delhi 110 001, India)
Publication Type: Journal: Article

Thatchill J, Whitehead GA: Indian Journal of Pediatrics: Nov 2011

Clotting Screen Requests in Pediatrics

Abstract

Coagulation parameters are routinely requested among all age-groups in pediatrics to identify abnormalities which may contribute to bleeding manifestations or thrombotic complications. These results are vital especially in the management of sick children although in some cases, they may be helpful in identifying those with inherited bleeding disorders and to confirm or exclude non-accidental injury. Despite the usefulness of these screening tests, it is important that the professionals who are responsible for the care of children interpret the results of these tests in the most accurate manner to avoid unnecessary further investigations and inappropriate management. 

Link to full text

J Thachil… – Indian Journal of Pediatrics, 2011
GA Whitehead Department of Child Health, Macclesfield General Hospital